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The phenyl R 7 group may be substituted with one or more substituents. In specific aspects of this embodiment, the revTetR protein comprises an amino acid substitution at a position selected from the group consisting of positions 59, 56, 53, 61, and 60 of SEQ ID NO: 32, and more particularly, selected from the group consisting of positions 59 and 56 of SEQ ID NO.; 32. We apologize for any inconvenience this may cause.

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